Peripheral nerve impairment is associated with a higher risk of dementia in older adults


  • Older adults with lower extremity peripheral nerve function loss, particularly sensory impairments, may be at a higher risk for dementia.

Why this matters?

  • Lower extremity peripheral nerve impairments are common among older adults; sensory function may be impaired in up to 50% of older adults. Preliminary evidence suggests it may also be more prevalent in those with cognitive impairment.

  • The association between peripheral neuropathy and dementia could inform clinical care and management of both patient populations, as well as help identify those who are susceptible to poor health outcomes.