Peripheral nerve impairment is associated with a higher risk of dementia in older adults

Takeaway

• Older adults with lower extremity peripheral nerve function loss, particularly sensory impairments, may be at a higher risk for dementia.

Why this matters?

• Lower extremity peripheral nerve impairments are common among older adults; sensory function may be impaired in up to 50% of older adults. Preliminary evidence suggests it may also be more prevalent in those with cognitive impairment.

• The association between peripheral neuropathy and dementia could inform clinical care and management of both patient populations, as well as help identify those who are susceptible to poor health outcomes.