Neurofilament light chain associated with disability and brain atrophy in MS

Serum neurofilament light chain (sNfL) is a useful marker of disability and brain atrophy related to multiple sclerosis (MS), researchers say.

“There is ample evidence that sNfL levels are associated with clinic-radiological measures of inflammatory disease activity and predictive of future disability and brain or spinal cord atrophy,” said Dr Elias Sotirchos of Johns Hopkins University in Baltimore, Maryland, USA. “However, evaluations of sNfL in large, heterogenous MS populations are limited.”