Biomarker predicts seizure freedom after epilepsy surgery in children

By combining data on excitability and connectivity, researchers have developed a biomarker that predicts surgical outcomes in children with drug-resistant epilepsy (DRE).

“In children with DRE, identifying the epileptogenic zone in the brain can be challenging, even with intracranial EEG” according to Dr Eleonora Tamilia and colleagues at the Harvard Medical School in Cambridge, Massachusetts, USA.

“As epileptogenicity is a complex property dependent on the interplay between excitability and connectivity, the ideal biomarker should account for both aspects.”